ArteFill is a PMMA (polymethylmethacrylate) filler designed to address facial wrinkles and folds with long-lasting results. The injectable contains tiny PMMA microspheres suspended in a collagen base that works in two phases: the collagen is absorbed over several months while the PMMA particles remain to provide ongoing support and volume. It is typically used for moderate to deep lines around the mouth, nasolabial folds, and other facial creases.

ArteFill works best for adults with moderate to deep facial wrinkles who want results that last significantly longer than traditional hyaluronic acid fillers. Ideal candidates understand that PMMA fillers are permanent and are committed to the specific look they create. A provider will assess skin type, depth of lines, and medical history during consultation to confirm suitability.

The appointment typically takes 30 to 60 minutes. Your provider will cleanse the treatment area and may apply numbing cream or use local anesthesia. ArteFill is injected into the dermis using a fine needle, with the provider carefully placing product to smooth wrinkles and restore volume. Some practitioners use a test dose approach, injecting a small amount and waiting several months before additional treatment to assess the final result.

Most people experience minimal downtime. Mild swelling, redness, and bruising at injection sites are common and typically fade within a few days. You can resume normal activities immediately, though avoiding strenuous exercise and heat for 24 to 48 hours is often recommended. Follow your provider's specific aftercare instructions.

Results develop gradually as the collagen component absorbs and the PMMA particles settle into place, with full effects visible over 3 to 4 months. Unlike temporary fillers, ArteFill results are considered permanent because the microspheres do not break down. If adjustments are desired, additional treatment can be layered, though reversal is not straightforward.